首页> 外文OA文献 >Esofagectomía transhiatal por vía abierta y vía laparoscópica para el cáncer de esófago: análisis de los márgenes de resección y ganglios linfáticos
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Esofagectomía transhiatal por vía abierta y vía laparoscópica para el cáncer de esófago: análisis de los márgenes de resección y ganglios linfáticos

机译:开放式和腹腔镜经食管癌食管癌切除术:切除切缘和淋巴结分析

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摘要

Surgical treatment of cancer of the oesophagus is associated with a high morbidity and mortality. Minimally invasive surgery has been proposed as an alternative to try to reduce these complications; however, at this time there are not many studies that evaluate the oncological validity of this method. The objective of this work is to give a preliminary audit of the results of our experience in both surgical techniques, with special emphasis on the oncopathological aspects (resection margins and lymph nodes). MATERIAL AND METHOD: Between April 2003 and February 2007, 40 patients diagnosed with distal oesophageal cancer were surgically intervened at Charing Cross Hospital, London, 24 open and 16 by laparoscopy in accordance with the surgeon responsible. Of these, 50% received neoadjuvant chemotherapy. Both groups were homogeneous for age, sex, ASA, tumour stage and tumour location. In all cases, the pathological tumour stage (TNM), the tumour distal margin, tumour proximal margin, tumour circumference and number of resected lymph nodes, were collected in a data base. RESULTS: The number of resected lymph nodes was similar in both groups; (19 for open and 18 for laparoscopy). The mean distal tumour margin for the group treated by open surgery was 4.9 cm compared to 4.3 in the group treated by laparoscopy (p = 0.578). The mean proximal tumour margin for the group treated by open surgery was 8.4 cm compared to 4.6 cm in the laparoscopy group (p = 0.004) and tumour circumference margin was positive in 11 patients (45%) belonging to the open group compared to 5 patients (33%) in the laparoscopy group (p = 0.519). CONCLUSIONS: In our experience, laparoscopic surgery for cancer of the oesophagus appears to show similar initial results to those of open surgery as regards the number of resected lymph nodes and resection margins.
机译:食道癌的外科手术治疗与高发病率和高死亡率有关。已经提出了微创外科手术作为减少这些并发症的替代方法。但是,目前尚无许多研究评估这种方法的肿瘤学有效性。这项工作的目的是对我们在两种手术技术中的经验结果进行初步审核,并特别强调肿瘤病理学方面(切除切缘和淋巴结)。材料与方法:在2003年4月至2007年2月之间,根据负责的外科医生,在伦敦查令十字医院对40例诊断为食道远端癌的患者进行了手术干预,分别在腹腔镜下进行了24例腹腔镜手术和16例进行了腹腔镜手术。其中,有50%接受了新辅助化疗。两组的年龄,性别,ASA,肿瘤分期和肿瘤位置均相同。在所有情况下,均在数据库中收集病理性肿瘤分期(TNM),肿瘤远端切缘,肿瘤近端切缘,肿瘤周长和切除的淋巴结数量。结果:两组切除的淋巴结数目相似。 (开放式为19,腹腔镜为18)。开放手术组的平均远端肿瘤切缘为4.9 cm,而腹腔镜手术组为4.3(p = 0.578)。腹腔镜手术组的平均近端肿瘤切缘为8.4 cm,而腹腔镜检查组为4.6 cm(p = 0.004),开放组的11例患者(45%)的肿瘤周缘切缘为阳性,而5例患者(33%)在腹腔镜检查组中(p = 0.519)。结论:根据我们的经验,就切除的淋巴结数目和切除切缘而言,腹腔镜手术治疗食道癌的初步结果似乎与开放手术相似。

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